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Drugs for Neurogenic Bladder Dysfunction Ryuji Sakakibara 1 , Setsu Sawai 1 , Tsuyoshi Ogata 1 1Neurology, Sakura Medical Center, Toho University Keyword: 神経因性膀胱 , 過活動膀胱 , 残尿 , 自律神経障害 , neurogenic bladder dysfunction , overactive bladder , post-void residual , autonomic dysfunction pp.623-629
Published Date 2023/5/1
DOI https://doi.org/10.11477/mf.1416202388
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Abstract

Urinary dysfunction includes an overactive bladder (OAB), post-void residual (PVR)/retention, or both entities. Brain diseases cause OAB, peripheral neuropathies are associated with significant PVR/retention, and multisystem atrophy/spinal cord diseases result in a combination of OAB and PVR/retention. Selective beta 3 adrenergic receptor agonists or anticholinergic agents are the first-choice treatment for OAB and clean intermittent self-catheterization, alpha-blocker and cholinergic stimulant therapy for significant PVR/retention. These therapies may be useful to maximize patients' quality of life and prevent serious complications, such as urosepsis or kidney dysfunction.


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電子版ISSN 1344-8129 印刷版ISSN 1881-6096 医学書院

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