BRAIN and NERVE Shinkei Kenkyu no Shinpo Volume 71, Issue 5 (May 2019)

Neuropsychiatric Systemic Lupus Erythematosus: From the Standpoint of Department of Neurology Atsuhiko Sugiyama 1 , Satoshi Kuwabara 1 1Department of Neurology, Graduate School of Medicine, Chiba University Keyword: 全身性エリテマトーデス , NPSLE , MRI , 線条体脳炎 , SLE , striatal encephalitis pp.459-471
Published Date 2019/5/1
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Neuropsychiatric manifestations in patients with systemic lupus erythematosus (SLE), termed neuropsychiatric SLE (NPSLE), encompass a wide variety of neurological and psychiatric characteristics. A neuropsychiatric event may precede an SLE diagnosis; therefore, physicians must screen for SLE in patients presenting with neuropsychiatric symptoms, if they are not already diagnosed with this condition. For assessing patients with SLE who present with neuropsychiatric symptoms, it is important to first determine whether the symptoms are caused by SLE (primary NPSLE), whether they are a complication of a therapy, or whether they are caused by other comorbidities. Accurate attribution of neuropsychiatric symptoms is vital for selecting therapeutic interventions.

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BRAIN and NERVE-神経研究の進歩
71巻5号 (2019年5月)
電子版ISSN 1344-8129 印刷版ISSN 1881-6096 医学書院