BRAIN and NERVE Shinkei Kenkyu no Shinpo Volume 68, Issue 4 (April 2016)

Dementia due to Endocrine Diseases Akiko Matsunaga 1 , Makoto Yoneda 2 1Department of Neurology, Faculty of Medical Sciences, University of Fukui Hospital 2Faculty of Nursing and Social Welfare Sciences, Fukui Prefectural University Keyword: 認知症 , 視床下部・下垂体系 , 甲状腺 , 副甲状腺 , 副腎皮質 , dementia , pituitary gland , thyroid , parathyroid , adrenal gland pp.399-405
Published Date 2016/4/1
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Endocrine diseases affecting various organs, such as the pituitary gland, the thyroid, the parathyroid, the adrenal glands and the pancreas, occasionally cause dementia. While Alzheimer's disease (AD) is the main cause of dementia in the elderly and is untreatable, dementia caused by endocrine diseases is treatable in most cases. However, patients with dementia associated with endocrine diseases show memory impairments similar to those found in AD, often leading to misdiagnoses. Patients with endocrine diseases often present with other characteristic systemic and neuropsychiatric symptoms caused by altered hormone levels. Such neuropsychiatric symptoms include involuntary movements, depression, seizures, and muscle weakness. In these cases, abnormalities in imaging and blood or urine tests are helpful in making a differential diagnosis. As delays in the diagnosis and treatment of these patients may cause irreversible brain damage, it is imperative for clinicians to carefully exclude the possibility of latent endocrine diseases when treating patients with dementia.

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BRAIN and NERVE-神経研究の進歩
68巻4号 (2016年4月)
電子版ISSN 1344-8129 印刷版ISSN 1881-6096 医学書院