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神経梅毒はペニシリン治療が確立されて大きく減少したものの,近年は増加傾向にある。実質型神経梅毒である進行麻痺は記憶障害,理解力・判断力の低下,異常行動など認知症症状をきたす疾患の1つであり,的確に診断,治療を行えば完治も可能な疾患であるためアルツハイマー病などの神経変性疾患による認知症との鑑別が重要である。神経梅毒の疫学,診断,治療を概説し,自験例を提示する。
Abstract
The incidence of neurosyphilis has declined dramatically because of the availability of penicillin. However, in recent years there has been an increase in the occurence of neurosyphilis. General paresis, a form of parenchymatous neurosyphilis, causes dementia. Some of the symptoms include loss of memory, poor understanding and judgment, and behavioral changes. It is important to distinguish general paresis from neurodegenerative disorders such as Alzheimer's disease, because with precise diagnosis and treatment, complete recovery is possible We describe epidemiological data, diagnosis and treatment of neurosyphilis as well as present our cases.
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