Prognostic Factors in Guillain-Barré Syndrome Kenichi Kaida 1 1Division of Neurology, Department of Internal Medicine, National Defense Medical College Keyword: ギラン・バレー症候群 , 予後 , ΔIgG , 免疫グロブリン静注療法 , Guillain-Barré syndrome (GBS) , prognosis , Erasmus GBS outcome score , Erasmus GBS Respiratory insufficiency score , ΔIgG pp.1411-1419
Published Date 2015/11/1
DOI https://doi.org/10.11477/mf.1416200313
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Clinical outcome of Guillain-Barré syndrome (GBS) is poorer than may be expected, despite recent applications of plasmapheresis and IVIg. Among prognostic factors of GBS, clinical factors are more useful compared to electrophysiological or biological factors. To improve the outcome of GBS patients with poor prognoses, a worldwide prospective survey (IGOS, International GBS Outcome Study) and a Japanese prospective GBS outcome study (JGOS) have been conducted. These surveys make it possible to define biomarkers for disease activity and recovery, and to develop prognostic models to precisely predict the clinical course and outcome in individual patients in the early stage of the disease.

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