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83歳,女性.数年来頻尿,膀胱刺激症状があり,1年前より近医で膀胱炎として治療をうけるも症状増悪したため当科受診.DIP,膀胱造影で,膀胱内腫瘤性病変はないが著明な萎縮膀胱であった.尿細胞診classV,生検で上皮内癌を認めたため,膀胱全摘術を行った.膀胱筋層は線維化が著明で,多数の肥満細胞が認められ,萎縮膀胱をきたした間質性膀胱炎に合併した上皮内癌と診断した.
A 83-year-old female patient was admitted suffering from pollakisuria and bladder irritability for the past several years. DIP and cystography showed contracted bladder without mass lesion in the bladder. Radical cystectomy was carried out, because urine cytology was class V and histopathological diagnosis of biopsied bladder mucosa was carcinoma in situ. Histopahological findings of surgical specimen showed remarkable fibrosis and significantly increased mast cell count in the detrusor muscle which were compatible with interstitial cystitis.
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