ホルモン化学療法後にDICと重症黄疸を発症し救命し得た前立腺癌

Prostate Cancer Accompanied with DIC and Severe Jaundice Who Was Able to Be Rescued:A Case Report

　症例は75歳，男性。前立腺低分化腺癌病期Cの診断でホルモン化学療法を施行した。前立腺腫瘍マーカーは正常範囲内であった。化学療法後3日目に，突然，播種性血管内凝固（以下，DIC）と重症黄疸を発症したが，適切な治療によりDICと黄痘は改善した。発症前後の臨床経過から，DICと黄疸の原因として抗癌剤の関与が考えられた。

In a 75-year-old man with prostate cancer stage C, we performed hormonechemotherapy (Flutamide 375mg/day, Goserelin acetate3.6mg/month, Cisplatin (CDDP)20mg/ day (day1), Etoposide (VP-16)50mg/day (day1-5)). Three days later, DIC and severe jaundice appeared. Meticulous treatment to DIC was performed and he re-coverd. It was thought DIC and severe jaundice were induced by administered drugs.