顆粒球コロニー刺激因子産生腎癌の1例

A CASE OF G-CSF-PRODUCING RENAL CELL CARCINOMA

　34歳，男性，主訴は血尿，右側腹部痛。CTにて右腎に径5cmの腫瘍を認めた。また著明な白血球増多症および血清顆粒球コロニー刺激因子の高値を認めたため，顆粒球コロニー刺激因子産生腫瘍を疑い腎摘出術を施行した。病理診断は腎細胞癌であり，免疫組織化学的染色で顆粒球コロニー刺激因子産生を証明した。

A case of G-CSF-producing renal cell carcinoma is presented. The patient was a 34-year-old man with the chief complaint of right back pain and macroscopic hematuria. Computed tomography revealed right renal tumor. Laboratory data showed marked leukocytosis and increased serum G-CSF. Right nephrectomy was performed and the pathological report showed renal cell carcinoma. lmmunohistochemical staining using anti-G-CSF antibody showed positive staining in the cancer cells.