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56歳,男子の高ゴナドトロピン血症を伴った右睾丸に発生した稀なライジッヒ細胞腫瘍。対側睾丸生検でライジッヒ細胞の過形成と思われる所見を認め,これら両側の病理組織学的変化は,中枢性の高ゴナドトロピン血症から惹起されたものではないかと考えた。また放射線治療後,末梢リンパ球染色体に数的構造的異常が発見されたが,これは放射線照射によるものと判定された。除睾術後2年3カ月現在健在である。
An unusual case of right testicular tumor with excessive serum gonadotropin in a 56-year-old man was reported. He had gynecomastia, and there was no history of undesceded testes. Familial history was not particular and his son and daughter were healthy. A high orchiectomy was performed in other clinic. Histopathological examination of this tumor revealed malignant Leydig cell tumor with central necrosis, pleomorchism and several mitosis. Tumor markers were within normal limits. In endocrine function tests, the serum LH-RH and testosterone levels were within normal limits, but the serum FSH level was 38.
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