テガフール・ギメラシル・オテラシルカリウム配合剤（TS-1）が奏効した尿路上皮癌

A case of TS-1 therapy effective to urothelial carcinoma

患者は73歳男性。2003年4月に左腎盂癌，前立腺癌に対して左腎尿管全摘，前立腺全摘術を施行。術後腎盂癌による左傍大動脈リンパ節転移が疑われ，全身化学療法を薦めるも拒否。5年間に同リンパ節は緩徐に増大した。その後，胃癌に罹患し，幽門側胃切除を行った際に同リンパ節の針生検を行った。病理診断は尿路上皮癌であった。胃癌の術後補助化学療法としてTS-1を投与したところ，同リンパ節は著明に縮小した。

Abstract A 73-year-old male with renal pelvic cancer had received left nephroureterectomy and radical prostatectomy for left renal pelvic and prostatic cancer in April,2003. Three months after the operation,a paraaortic lymph node swelling was found in his follow up CT study,and the lymph node metastasis of renal pelvic cancer was suspected. Although we recommended him to receive chemotherapy,he refused our proposal. The lymph node had grown slowly for 5 years. Then he suffered from gastric cancer in June,2008 and at the gastric surgery needle biopsy was performed for the enlarged lymph node,which was found to be metastasis of urothelial cancer. The lymph node had been reduced in size dramatically by TS-1 administration as adjuvant therapy for gastric cancer.