肺癌を合併した菌状息肉症の1剖検例

AN AUTOPSY CASE OF MYCOSIS FUNGOIDES WITH LUNG CANCER

　菌状息肉症は1932年にAlibertが報告して以来，その特異な臨床像および組織学的所見から，多くの皮膚科医および病理学者の研究の対象としてとりあげられているが，その割に剖検例の報告が少なく，病因についても，未だ種々意見が別れている．最近我々は，菌状息肉症のいわゆる古典型と考えられる症例で，4年間にわたり経過を観察し，この間右肺腺癌の合併を認めた症例を剖検する機会を得たので報告する．

Lung canser developed in a 71-year-old woman with mycosis fungoides (the plaque stage). The histologic picture of the skin showed the presence of Pautrier "microabscess" and the patchy infiltration of atypical reticulum cells (mycosis cells), lymphocytes, eosinophils and Sternberg-Reed giant cells. These findings resemble to histologically "Hodgkin's disease".

While many authors still adhere to the view that mycosis fungoides represnt a granuloma, genera-lly it is regarded as a lymphoma. If mycosis fungoides is represented as a malignant tumor, this case is regarded as a double development of malignant tumor.