結合織母斑の経験，あわせてその臨床的分類ならびに病理について

EXPERIENCE OF CONNECTIVE TISSUE NEVUS, WITH SPECIAL REFERENCE TO ITS CLASSIFICATION AND PATHOLOGY

　結合織母斑はNaevus elasticus regionismammariae（Lewandowsky）^1），Pflastersteinförmige Bindegewebsnaevi（Lipschütz）^2），Dystrophie élastique folliculaire thoracique（héréditaire？）（With et Kissmeyer）^3），Naevuspseudocoloïde périfolliculaire（Montpellier etLacroix）^4）等の名称で報告されてきたが，1926年Gutmann^5）によりこの疾患の概念が明確にされ，さきにSachs^20）よつて唱えられたBindegewebsnaeviの称呼を用いるに至つて，この名称が一般化するに至つた。本邦にあつては，昭和3年山本^6）の本症の単発例の報告をもつて嚆矢とし今日迄23例^7）〜19）が報告されているにすぎず，比較的稀な疾患に属するといえる。

　最近，著者は限局性鋪石状並びにに限局性斑状とも称すべき所見の結合織母斑を各1例経験したので記載し，併せて本邦に於ける本症の統計的観察並びに本症の疹型について文献的考察を加えたいと思う。

On the basis of reported 23 cases and the author's own 2 cases of connective tissue nevus in Japan, the authors presented a following classification.

1. Localized type. a) Shagreen type. b) Macular type.

2. Systematized nodular type.

3. Disseminated or generalized type.

Case 1 : Localized shagreen type.

A 35-year-old man had the lesion at birth. On his first visit, there was a palm-sized lesion on the right chest composed of numerous discrete papules, which were flat-topped, miliary to ricegrain-sized, round or polygonal and fawn-colored.

Histologic specimens showed proliferation of thickened and homgenous collagen fibers in the upper and middle dermis, where elastic fibers disappeared. Arrector pili-like muscle bundles were scattered in the middle dermis.

Case 2 : Localized macular type.

A 20-year-old man noted the lesion in his childhood. On his first visit, there were four plapues in the lumbar region, each of which was 5 cm. in diameter and composed of elevated, normal or yellowish-white colored nodules or tumors in the size of a bean.