雑誌文献を検索します。書籍を検索する際には「書籍検索」を選択してください。

検索

書誌情報 詳細検索 by 医中誌

Japanese

A Case of Gastric Scirrhous Carcinoma Presenting as Aggressive Fibromatosis in the Whole Neck Hiroyuki Wakisaka 1 1Department of Otolaryngology, Ehime University School of Medicine pp.445-449
Published Date 1998/6/20
DOI https://doi.org/10.11477/mf.1411902738
  • Abstract
  • Look Inside

A 51-year-old woman complained of mild dysphagia and a diffuse swelling of the neck. There were no abdominal symptoms. Biopsy specimens taken from the neck and inguinal resion showed diffuse fibromatosis and no evidence of malignant changes. Serum examination revealed elevated bFGF and PDGF levels and positive antinuclear,anti-ssDNA and anti-dsDNA antibodies. Autoim-munological mechanism was considered to be most likely etiology. However, immunosuppressive ther-apy failed to relieve her symptoms. Three months after occult blood was detected in stool and gastric fiberscopy confirmed a diagnosis as gastric scirr-hous carcinoma. She died of multiple organ failure due to carcinoma 6 months after admission. Meticu-lous reexamination of the biopsy specimen reveal-ed the scattered distribution of highly degenerat-ed cancer cells. Elevated serum levels of bFGF and PDGF produced from cancer cells in the neck probably contributed to formation of progres-sive fibromatosis.


Copyright © 1998, Igaku-Shoin Ltd. All rights reserved.

基本情報

電子版ISSN 1882-1316 印刷版ISSN 0914-3491 医学書院

関連文献

もっと見る

文献を共有