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はじめに
聴神経鞘腫に対する放射線治療としては,コバルト1回大量照射であるガンマナイフによる定位的放射線外科(stereotactic radiosurgery:SRS)が国内でも1990年より数か所の施設で行われているが,われわれは1992年より本邦では唯一,リニアックを用いた分割照射である定位的放射線療法(stereotactic radiotherapy:SRT)を施行している。今回SRTの腫瘍制御率,合併障害,聴力障害につきガンマナイフとの報告1〜4)の比較を検討したので報告する。
We analyzed forty one patients with acoustic neuroma treated by SRT giving 36 Gy in 20 frac-tions to 48 Gy in 23 fractions during 1991 and 1997, and found a sterilization of tumor size in 97.6%. Twenty-six patients had measurable hearing before and after SRT and 43.5% of patients showed change in pure tone average less than 10 dB, 82.6% less than 20 dB at the last follow-up examination. Facial and trigeminal nerve function was evaluated in 41 patients. Transient facial weakness developed in 4.8% and trigeminal neuropathy in 9.6% of irradiat-ed cases. We consider that SRT complications are less than that of gamma-knife, although the longer follow-up period should be needed.
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