消化管ホルモン陽性の鼻腔原発腸管型腺癌の1症例

Intestinal-type Adenocarcinoma of the Nasal Cavity; Report of a Case and It's Immunohistological Study

I．はじめに

　鼻副鼻腔領域における悪性腫瘍は上顎洞に最も多く発生し，組織学的には大部分が扁平上皮癌である。今回われわれは比較的稀れとされている鼻腔原発腸管型腺癌を神験した。本症例につき組織学的検討を有い，文献的考察を加え報告する。

A 51-year-old man was complaining of left nasal obstruction and nasal bleeding,. Biopsy specimens from a tumor filling in the left nasal cavity showed adenocarcinoma. After preoperative chemotherapy, left lateral rhinotomy was carried out. The tumor was totally removed and the postoperative course was satisfactory.

I mmunohistochernically, intestinal polypeptide hormone-positive cells were identified. Squamous metaplasia and intestinal hyperplasia with goblet cells and Paneth cells were observed at the non-neoplastic epithelium. These findings are important to confirm nasal adenocarcinoma.