舌根部過誤腫の1例

A case of hamartoma arising from the base of the tongue

I．はじめに

　過誤腫とは，ある器官に固有の組織成分の一部が過剰増生した先天異常である^1）。肺，脾，肝，腎，膵にはしばしば発生するといわれるが，口腔領域の報告例は比較的稀で，小児の口腔腫瘤のうち6～11％を占めるといわれる^2～4）。今回われわれは，舌根部過誤腫の1例を経験したので，その臨床的特徴や発生病態について文献的考察を加えて報告する。

Hamartoma is a tumor-like malformation in which various tissue components with various degrees of differentiation are abnormally arranged. A 7-month-old girl presented with postnatal snoring and coughing on suckling. Physical examination,x-ray and magnetic resonance imaging revealed a forefinger-tip-sized pedunculate mass arising from the base of the tongue. The mass was transorally removed by YAG-laser. Pathological diagnosis of the surgical specimen was hamartoma composed of a mixture of salivary glands,adipose tissue,connective tissue,and smooth muscle. The patient's symptoms completely subsided postoperatively,and she was currently free from disease 5 years after surgery. Reported cases of hamartomas of the base of the tongue were reviewed from the viewpoint of developmental biology.