網膜色素線条に伴った傍中心窩脈絡膜新生血管に対する放射線治療

in a case of angioid streaks

　52歳男性が2か月前からの左眼視力低下で受診した。矯正視力は右1.2，左0.8であった。両眼に網膜色素線条があり，左眼では色素線条が中心窩に達し，中心窩に脈絡膜新生血管があった。皮膚科での生検で弾力線維性仮性黄色腫が証明された。2か月後に左眼視力が02に低下した。6MVでの放射線照射を1回2Gyで2週間，総量20Gyを左眼後極部に行った。以後4か月間，左眼視力は0.2に維持され，脈絡膜新生血管の広さに変化はなく，病巣は平坦化し，病巣からの蛍光漏出は低下し，照射による副作用は起こっていない。

A 52-year-old male presented with reduced visual acuity in his left eye since 2 months before. His corrected visual acuity was 1.2 right and 0.8 left. Both eyes showed angioid streaks. The pigment streak ran through the fovea associated with subfoveal neovascularization in his left eye. Biopsy of the skin showed pseudoxanthoma elasticum. After the left visual acuity decreased to 0.2 2 months later, the left eye received external radiation at the daily dosis of 2 Gy totalling 20 Gy. During the ensuing 4 months, the left visual acuity has stabilized at 0.2. The subfoveal lesion became flattened, showed decreased dye leakage by fluorescein angiography, and the choroidal neovascularization showed no increase in size. There has been no complication due to radiation.