A case of central retinal vein occlusion associated with platelet hyper-aggregation Takuya Hasegawa 1,2 , Yoshihide Nishimura 1 , Kenji Matsushita 1 , Norio Okamoto 3 , Masakatsu Fukuda 3 1Dept of Ophthalmol, Matsuyama Red Cross Hosp 2Dept of Ophthalmol, Osaka Rosai Hosp 3Dept of Ophthalmol, Osaka Teishin Hosp pp.1312-1316
Published Date 1999/6/15
DOI https://doi.org/10.11477/mf.1410906442
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A 72-year-old female presented with sudden visual loss in her left eye. She had been receiving peroral warfarin for ventricular fibrillation since 15 years before. Funduscopy and fluorescein angiography showed nonischemic hemicentral retinal vein occlusion in the inferior hemisphere in the affected eye. Laboratory tests showed a hypocoagulable state with thrombopenia at 36% with increased platelet aggregation activity. Continuous antiplatelet treatment with anticoagulation agents induced improvement of visual acuity from the initial 0.2 to 0.6. This case illustrates that central retinal vein occlusion may develop associated with platelet hyper-aggregation and that it may respond to antiplatelet treatments.

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