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(25D-3) 治療的エキシマレーザー表層角膜切除術(phototherapeutic keratectomy)後,2年以上経過観察できた20例26眼(顆粒状角膜変性症14眼,帯状角膜変性7眼,格子状角膜変性症3眼.膠様滴状角膜変性症1眼,再発性角膜びらん1眼)の長期経過と再発率を検討した。術後2年時では全症例で術前以上に矯正視力が改善をした。再発は,顆粒状角膜変性症に14眼中1眼(7%),帯状角膜変性では7眼中4眼(57%)にあったが,極めて軽度であり,視力低下はなかった。本手術は角膜表層病変に対し視力的には有効な手技であるが,再発は他の治療法と同様,避け得ないものと考えられる。
We reviewed 26 eyes in 20 patients who received photokeratectomy with excimer laser and who could be followed up for 2 years or longer. The causative lesion comprised granular dystrophy 14 eyes, band keratopathy 7 eyes, lattice dystrophy 3 eyes, gelatinous drop-like dystrophy 1 eyes and recurrent corneal erosion 1 eye. At 2 years after treatment, the corrected visual acuity had improved over the pretreatment level in all the eyes. The corneal lesion recurred in 5 eyes including 4 eyes of band keratopathy and 1 eye of granular dystrophy. The recurrence was slight and did not affect the visual acuity. The present therapeutic modality was thus beneficial regarding visual acuity but did not always prevent recurrence in progressive corneal lesions.
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