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White dot fovea Ken-ichi Yokotsuka 1 , Yo Kamei 1 , Shoji Kishi 1 1Dept of Ophthalmol, Gunma Univ Sch of Med pp.983-989
Published Date 1996/5/15
DOI https://doi.org/10.11477/mf.1410904911
  • Abstract
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We identified a new foveal lesion mimicking idiopathic macular hole in 48 eyes of 25 cases. The foveal lesion was characterized by the presence of numerous white granules on the surface of foveal depression. The white granules were distributed either diffusely or along the foveal margin forming a grayish ring. We tentatively named this condition as 'white dot fovea'. The cases included 9 men and 16 women. The ages ranged from 53 to 73 years, mean 64 years. The condition was bilateral in all cases except two. There were no subjective symptoms nor visual disturbances. The condition was best seen by a scanning laser ophthalmoscopy using argon blue laser as the light source. The white granules numbered from 100 to 300 per eye. Each granule was about 5 μm in diameter.

In our earlier observation by scanning electron microscopy in autopsy eyes, foveal granules simulating the white dots were observed in 5 of 30 senile eyes. The number of the granules ranged from 100 to 200 and its diameter from 5 to 20 μm. The granules had multiple protrusions with cilia, which resembled glial cells. We postulate this glia-like structure in autopsy eyes as a couterpart of clinically observed 'white dot fovea'.

Since white dot fovea has been found by chance observation, its actual incidence seems to be high. This new clinical entity merits due attention in the differential diagnosis of macular holes.


Copyright © 1996, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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