雑誌文献を検索します。書籍を検索する際には「書籍検索」を選択してください。

検索

書誌情報 詳細検索 by 医中誌

Japanese

Effect of tissue plasminogen activator on re-elevated intraocular pressure in the early postoperative period after trabecurectomy Tomoko Nagasaka 1 , Fumitaka Ando 1 , Hisao Furuta 1 , Yukari Kuroda 1 , Midori Furui 1 , Hidenori Ishihama 1 1Dept of Ophthalmol, National Nagoya Hosp pp.1201-1205
Published Date 1995/6/15
DOI https://doi.org/10.11477/mf.1410904376
  • Abstract
  • Look Inside

We studied the effect of tissue plasminogen activator (tPA) on re-elevated intra-ocular pressure in the early postoperative period after trabeculectomy. Twenty-five μg of tPA was injected into the anterior chamber of 20 eyes of 19 glaucoma patients, and intra-ocular pressure before and after injection of tPA, the period from operation to tPA injection, and the prognosis compared with eyes in which tPA was not used were estimated. Mean IOP before injection was 32.9 mmHg, and that on the first and second day after injection was 17.4 mmHg and 17.0 mmHg, respectively. The efficacy in achieving an IOP of 20 mmHg or below was 77% in the group injected within 10 days, as compared with 17% in the group injected after 11 days. The prognosis for the cases in which tPA was used was better than in those without it 2 weeks and 3 months after the operation. We think this is a good procedure for avoiding closing of the bleb in the early period after trabeculectomy. The critical period for this procedure seems to be 10 days after trabeculectomy.


Copyright © 1995, Igaku-Shoin Ltd. All rights reserved.

基本情報

電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

関連文献

もっと見る

文献を共有