網膜静脈閉塞症の全身的因子

Systemic features in central and branch retinal vein occlusion

　対象は網膜静脈閉塞症新鮮例59例—中心静脈閉塞15例（男10例，女5例），分枝閉塞44例（男女，各22例）—で，平均年齢は中心静脈閉塞65.2歳，分枝閉塞60.2歳，前者は他報告に比し高齢であった。年齢，性別，季節的変動，貧血，血清蛋白分画，高血圧，肥満度，喫煙，アルコール嗜好において，中心静脈閉塞と分枝閉塞間に差はなかった。ただし，中心静脈閉塞では，対照に比し，血清アルブミン・グロブリン比の減少，α₁およびα₂グロブリンの増加がみられた。

　網膜静脈閉塞症において，高血圧との関係が再確認された。つまり，血圧正常で降圧剤服用中の人や高血圧既往者を含むと中心静脈閉塞の80％，分枝閉塞の61％を占めた。しかし，喫煙やアルコール嗜好者は少なく，網膜静脈閉塞と直接の深い関連はないと考えられた。

Systemic factors were evaluated in 59 patients with retinal vein occlusions during the foregoing 7 -year period. The series included 15 cases of central retinal vein occlusion (CRVO) , 10 males and 5 females, and 44 cases of branch one (BRVO), 22 males and females each. The age of patients with CRVO averaged 65.2 years.

No significant differences were present between CRVO and BRVO regarding age, sex, erythrocyte count, serum proteins, systemic blood pressure, body weight, smoking or drinking habits. Caseswith CRVO showed decrease in albumin-globulin ratio in the serum and increase in α₁ and α₂ globulins as compared with the control. Current or previous hypertension was present in 80% of cases with CRVO and in 61% of those with BRVO. In female patients, 92% were nonsmokers and 88% were nondrinkers. In male patients, 47% were nonsmokers and 43% were nondrinkers. Smoking or drinking habits seemed to be not related with retinal vein occlusions.