1眼に網膜血管炎，他眼にAPMPPEを発症したクローン病の1例

Retinal vasculitis in one eye and APMPPE in the fellow eye associated with Crohn's Disease

　直腸型クローン病の診断を受け，小腸狭窄増強のために小腸切除及び人工肛門造設術を受けた後4年4か月を経過して右眼に網膜血管炎による血管閉塞が発症し，その後左眼に急性後部多発性小板状色素上皮症（APMPPE）を発症した27歳男性の症例を経験した。右眼には初診時すでに新生血管が生じ，硝子体出血を繰返したため，レーザー網膜光凝固及び硝子体手術を施行し，視力の改善を得た。左眼は3か月の自然経過で，網膜に軽度の脱色素斑を残し視力は改善した。クローン病の合併症として網膜血管および脈絡毛細管板の血管に炎症が生じたものと考えられた。

A 27-year-old male had been diagnosed as Crohn's disease and undergone surgical excision of the involved terminal ileum 4 years 4 months before. He presented with retinal vasculitis associated by multiple retinal nonperfusions areas and newly formed vessels in the right eye. He was treated by laser photocoagulation and eventual vitrectomy for recurrent vitreous hemorrhage. Ten months later, he developed an episode of acute posterior multifocal placoid pigment epitheliopathy (AP-MPPE) in the left eye. APMPPE resolved 3 months later leaving permanent alterations in the retinal pigment epithelium. It appeared that the retinal vasculitis and APMPPE were hitherto unkown extraintestinal manifestations of Crohn's disease.