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Evaluation of antithrombotic therapy in patients undergoing trabeculotomy Kaori Kobayashi 1 , Rikiya Ihara 1 , Ryo Nagaoka 1 , Shusaku Mizoguchi 1 , Takashi Okayasu 1 , Morio Okada 1 1Department of Ophthalmology, Kurashiki Central Hospital pp.865-870
Published Date 2019/7/15
DOI https://doi.org/10.11477/mf.1410213196
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Abstract Purpose:To evaluate the impact of antithrombotic drugs on the outcomes and complications in trabeculotomy for glaucoma.

Subjects and methods:We reviewed the data on 111 patients(111 eyes)who had undergone initial trabeculotomy. The series included 68 males and 43 females. Mean age was 69.0±14.2 years. We divided them into two groups:patients who received antithrombotic therapy before and during throughout surgery(medication group)and those who did not receive antithrombotic therapy(non-medication group). The postoperative intraocular pressure(IOP)and complications were compared between the two groups.

Results:The medication group included 23 patients(20.7%). The non-medication group included 88 patients(79.3%). Preoperative and postoperative IOP averaged 23.3±5.4 mmHg and 14.9±3.6 mmHg in the medication group and 26.5±8.4 mmHg and 16.1±5.4 mmHg in the non-medication group. The differences were not significant(p=0.6). Anterior chamber hemorrhage of 1 mm or higher was found in 15 patients in the medication group and 40 patients in the non-medication group. The difference was not significant(p=0.2). Hyphema disappeared after 6.0±4.0 days in the medication group and 4.0±3.0 days in the non-medication group. The difference was significant(p=0.0154). Irrigation of the anterior chamber was required in 3 patients(13.0%)in the medication group and 1 patient(1.1%)in the non-medication group. The difference was significant(p=0.0275).

Conclusion:Patients who continued antithrombotic therapy at the time of trabeculotomy required more time before hyphema disappeared, and had increased need for irrigation of the anterior chamber. Postoperative IOP was not significantly different between the two groups.


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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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