Japanese

One-year outcome of intravitreal aflibercept for wet-type age-related macular degeneration Shigehiro Iwabuchi 1 , Chiaki Mitsui 1 , Hideaki Okawada 1 , Makoto Zenno 1 , Haruo Takahashi 1 1Department of Ophthalmology, Showa University School of Medicine pp.1079-1082
Published Date 2016/7/15
DOI https://doi.org/10.11477/mf.1410211876
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Abstract Purpose: To report the one-year outcome of intravitreal injection of aflibercept for wet-type age-related macular degeneration(AMD).

Cases and Method: This retrospective study was made on 28 eyes of 27 patients who received intravitreal injection of aflibercept for AMD during one year through April 2014. The series comprised 17 male and 11 female eyes. The age averaged 77 years. Nine eyes were treatment-naive and 19 eyes had received previous treatments including ranibizumab. AMD was exudative in 22 eyes and polypoidal choroidal vasculopathy in 6 eyes. Visual acuity and central retinal thickness were evaluated one year after start of treatment.

Results: Visual acuity was maintained without significant improvements as a whole. There was no difference in visual outcome between eyes with or without past treatments. Central retinal thickness improved in both types of AMD.

Conclusion: There was no deterioration in visual acuity one year after start of intravitreal aflibercept for wet-type AMD. The therapeutic response was the same between eyes that received aflibercept for the first time and eyes with previous similar treatments.


Copyright © 2016, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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