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Underlying severe heart disease in a fatal case due to anaphylaxis following intravenous fluorescein injection Mariko Hasegawa 1 , Shoichiro Shirai 1 , Yumiko Sakakibara 1 , Hiroaki Nishihara 1 , Tomohiro Mizuno 1 , Aya Inagaki 1 , Kenshin Naruse 2 , Matsuyoshi Maeda 3 1Dept of Ophthalmol, Toyohashi Mun Hosp 2Dept of Cardiol, Toyohashi Mun Hosp 3Dept of Pathol, Toyohashi Mun Hosp pp.523-527
Published Date 2015/4/15
DOI https://doi.org/10.11477/mf.1410211299
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Abstract. Purpose:To report a fatal case of anaphylaxis caused by intravenous fluorescein found a severe heart disease. Case:A 65-year-old male presented with vitreous hemorrhage and branch retinal vein occlusion in the left eye. Findings:In the first session of fluorescein angiography(FA), no adverse reaction occurred. The second FA was performed 7 months later. 2 minutes after the administration of intravenous fluorescein, the patient showed anaphylactic reaction. Despite of quick and proper treatment, the patient entered cardiopulmonary arrest. Following intensive care failed to induce recovery of hemodynamics, and he died after 2 days. Autopsy revealed severe cardiac hypertrophy, suggesting that his cardiac dysfunction was the main factor of poor response to critical care. Conclusion:Prior to FA, detailed interview about patient's condition is necessary. Screening test for heart disease should to be done as required.


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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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