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Epstein-Barr virus-specific antibodies in patients with Vogt-Koyanagi-Harada disease Tomohiko Kohdoh 1 , Mitsuko Sunakawa 1 , Ikki Arai 1 , Yu Jian Zhang 2 , Satoki Okinami 3 1Dep. of Ophthalmol., Fac. of Med., Kyoto Univ. 2Dept. of Ophthalmol., Guanzhong Chin. Med. Coll. 3Dept. of Ophthalmol., Tenri Hosp. pp.1245-1248
Published Date 1985/10/15
DOI https://doi.org/10.11477/mf.1410209555
  • Abstract
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We evaluated the antibody titers specific for Epstein-Barr virus in 23 patients with Vogt-Ko-yanagi-Harada disease, including 11 with Vogt-Ko-yanagi disease and 12 with Harada disease. Patients with Vogt-Koyanagi disease showed high values in the geometric mean titers of anti-viro-capsid-anti-gen than control and patients with Harada disease. Patients with Harada disease showed lower values in the geometric mean titers of anti-Epstein-Barr-virus nuclear antigen than control and patients with Vogt-Koyanagi disease.

These data suggest that there may be an immu-nological difference between Vogt-Koyanagi disease and Harada disease, although Vogt-Koyanagi dise-ase and Harada disease are included in the same clinical entity.

The difference between the pattern of antibodies in patients with Vogt-Koyanagi dise-ase and those with Harada disease were found to resemble the difference between the antibody pat-terns in anterior uveitis and pan-uveitis reported previously.


Copyright © 1985, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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