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特集 第35回日本臨床眼科学会講演集 （その3）
学会原著
スギ花粉症治療薬の定量的効果判定
Quantative therapeutic efficacy of Ketotifen®, eye drops for allergic conjunctivitis
三国 郁夫
1
,
外川 国人
2
,
水島 規子
2
Ikuo Mikuni
1
,
Kunihito Togawa
2
,
Noriko Mizushima
2
1東海大学医学部眼科学教室
2東海大學薬剤部
1Department of Ophthalmology, School of Medicine, Tokai University
2Pharmacy, School of Medicine, Tokai University
pp.573-576
発行日 1982年6月15日
Published Date 1982/6/15
DOI https://doi.org/10.11477/mf.1410208604
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通年性のスギ花粉症患者10例に，非発作期に誘発試験を行い，0.08％Ketotifen®点眼薬の定量的効果判定を行った。有効率は80％であった。点眼時一過性のしみる感じが30％にあった。
Ten patients suffering from seasonal Japanese cedar pollinosis were tested for the therapeutic efficacy of Ketotifen® eyedrops during the quies-cent period. Ketotifen® (HC20-511) possesses a structure similar to benzocycloheptathiophene and is claimed to exert anti-histamine, anti-anaphy-lactic and suppressive effects of liberation of me-diators.
A single drop of Ketotifem®, was instilled in the right eye followed by instillation of pollen extract 5 minutes later. The left eye was tested by a similar procedure by instilling placebo solution as substi-tute for Ketotifen®.
Copyright © 1982, Igaku-Shoin Ltd. All rights reserved.
