マイトマイシンC点眼によると思われる強膜軟化症症例について

Scleromalacia presumably due to Mitomycin C instilation after Pterygium excision

緒　言

　翼状片術後再発の予防にマイトマイシンC点眼を行ない，強膜に損傷をきたす症例をみることについては，既に報告^5,6）してきたところであるが，今回更に6症例を経験し，この中5例については強膜移植を行なつたので追加報告する。

Six cases of scleromalacia following Mitomycin C instillation after pterygium surgery are repor-ted. Five of them were treated by covering the lesion with preserved scleral homograft and fa-vorable results were obtained in all but one, in whom necrotizing scleritis progressed after scleral transplantation until all the sclera was involved and corneal ulcer developed. Scleromalacia due to topical Mitomycin C is an insidiously pro-gressive condition and shows poor tendency for spontaneous healing. Once scleromalacia occurs, it is recommended to bare the affected area and to restore the defect by supplemental tissue.