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Japanese

An ophthalmic solution of "Sinomin" (A long acting sulpha-drug) I. Suzuki 1 , A. Nishi 1 1Osaka Prefectural Hospital pp.1067-1073
Published Date 1960/6/15
DOI https://doi.org/10.11477/mf.1410206984
  • Abstract
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An ophthalmic solution of "Sinomin" is prepared with the sodium salt of "Sinomin" (5-methyl-3-sulfanilamido-isoxazole) in 4 and 10%. Results of its stabilities and efficacy in clinical cases are as follows :

1) pH of 4 and 10% solution are 8.9 and 9.1 respectively. After storage at room tempera-ture for 1 month the pH decreases to some extent but antibacterial activity does not show any decrdase in vitro. The solution merely becomes slightly yellowish but shows no re-markable changes macroscopically.


Copyright © 1960, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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