抗精神病薬リスペリドン内服患者にみられた術中虹彩緊張低下症候群の3例

Intraoperative floppy iris syndrome in three cases receiving risperidone, an antipsychotic agent

要約　目的：抗精神病薬リスペリドンの内服履歴がある症例に白内障手術を行い，術中虹彩緊張低下症候群（intraoperative floppy iris syndrome）が生じた3症例の報告。対象：過去68か月間に当科で白内障手術を行った症例を対象とした。結果：リスペリドン内服の履歴は6例11眼にあり，うち3例5眼（45％）に術中虹彩緊張低下症候群があった。内訳は，男性が2例3眼，女性が1例2眼であった。年齢は，それぞれ69，71，75歳であった。結論：非定型抗精神病薬リスペリドンの内服既往がある症例では，白内障手術の際，術中虹彩緊張低下症候群の原因になりうる。

Abstract.　Purpose：To report intraoperative floppy iris syndrome in 3 cases who had a history of treatment with systemic risperidone, an antipsychotic agent. Method：We reviewed cases who received cataract surgery by us during the past 68 months. Results：History of systemic risperidone was present in 11 eyes of 6 cases. Intraoperative floppy iris syndrome was present in 5 eyes of 3 cases（45％）. The series comprised 3 eyes of 2 males and 2 eyes of one female. They were aged 69, 71 and 75 years respectively. Conclusion：Cataract patients with past history of risperidone intake may manifest intraoperative floppy iris syndrome.