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非穿孔性線維柱帯切除術(nonpenetrating trabeculectomy)の成績を評価した。対象は40例50眼で,内訳は原発開放隅角緑内障33眼,正常眼圧緑内障7眼,続発緑内障4眼,その他であり,平均年齢は71.6±9.0歳である。11眼には通常の非穿孔性線維柱帯切除術,39眼にはこれに深層強膜切除を加えた変法を用いた。30眼には白内障手術と眼内レンズ挿入術を併用した。術後観察期間は平均10.0±4.2か月であった。術前眼圧は平均20.7±4.6mmHgであり,術後は最長15か月後までの各時点での平均眼圧が15mmHg以下であった。非穿孔性線維柱帯切除術とその変法,ならびに単独手術と白内障同時手術の間には,眼圧下降効果に有意差がなかった。濾過胞感染や過剰濾過に伴う合併症はなかった。眼圧下降が不十分な11眼にヤグレーザーによる隅角穿孔術を行い,有意な眼圧下降が得られた。非穿孔性線維柱帯切除術は緑内障に対する安全で有効な術式であると結論される。
We performed nonpenetrating trabeculectomy(NPT)on 50 eyes of 40 patients. The series comprised primary open-angle glaucoma 33 eyes,normal-tension glaucoma 7 eyes,secondary glaucoma 4 eyes and others. Their ages averaged 71.6±9.0 years. Eleven eyes received standard NPT and 39 eyes received additional deep sclerotomy. Thirty eyes received cataract surgery with intraocular lens implantation. Cases were followed up for an average of 10.0±4.2months after surgery. The intraocular pressure(IOP)averaged(20.7±4.6mmHg)before surgery. For 15months after surgery,the averaged IOP remained below 15mmHg. There was no significant difference in hypotensive effect between NPT alone and additional sclerotomy,not between glaucoma surgery alone and additional cataract surgery. There was no instance of bleb infection or overfiltration. Eleven eyes with insufficient hypotensive effect received goniopuncture using Nd:YAG laser with significantly decreased IOP. The findings show that nonpenetrating trabeculectomy is safe and effective for glaucoma.
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