未熟児網膜症治療の検討

Review of retinopathy of prematurity in our institution

目的：船橋中央病院での未熟児網膜症の発症と治療の状況の報告。対象と方法：過去27か月間に当院の新生児集中治療室に入院し，眼科的に精査した175例の診療録を検索した。結果：33例（19％）に未熟児網膜症が発症した。光凝固などの治療を要した重症例は6例（3.4％）であった。以下の因子が未熟児網膜症の発症に有意な関連があった。出生体重，在胎週数，酸素投与期間，仮死，光線療法，未熟児貧血，輸血，全身感染症，外科手術，呼吸窮迫症候群がそれである（p＜0.01）。結論：当院での未熟児網膜症については，他施設の報告よりも発症率と治療率がやや低めである。

Purpose：To report the current status about occurrence and treatment of retinopathy of prematurity（ROP）in our hospital. Cases and Method：This retrospective study was made on 175 infants who were admitted to the Neonatal Intensive Care Unit and who received detailed ophthalmological examinations. Results：ROP developed in 33 infants（19％）. Six infants（3.4％）with advanced ROP needed treatment including photocoagulation. Following items were significantly correlated with onset of ROP（p＜0.01）：birthweight,gestational age,duration of oxygen inhalation,fetal distress,phototherapy,anemia,blood transfusions,infection,surgery and respiratory distress syndrome. Conclusion：Incidence and severity of ROP in our hospital were lower than those reported from other institutions.