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Four cases of adult-onset vitelliform foveomacular dystrophy Noriko Shizukawa 1 , Hiroko Imaizumi 1 , Utako Okushiba 1 , Muneyasu Takeda 1 1Dept of Ophthalmol,Sapporo City General Hosp pp.1601-1608
Published Date 2005/9/15
DOI https://doi.org/10.11477/mf.1410100153
  • Abstract
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We observed four bilateral cases of adult-onset vitelliform foveomacular dystrophy. One was a 47-year-old female. The other three were males aged 47,53 and 70 years. Corrected visual acuity was 0.1 to 0.4 in 3 eyes,0.5 to 0.9 in 2 eyes,and 1.0 or over in 3 eyes. Indocyanine green(ICG)angiography showed hypofluorescence in the area of vitelliform lesion,suggesting blockage by accumulated retinal pigment epithelial(RPE)cells. It showed moderate hyperfluorescence around the vitelliform lesion,suggesting staining by ICG dye. Optical coherence tomography(OCT)showed thickening of RPE layer and presence of high-reflective layer inner to it. These findings were consistent with past reports and were interpreted as accumulation of RPE cells and deposit in the subretinal layer. Cystoid macular edema(CME)was present in both eyes of 53-year-old male. This complication has not been reported in past literature.


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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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