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A case of vitamin A deficiency four years after surgery for colon cancer Ayumi Matsuo 1 , Takahiro Hiraoka 1 , Toshiyuki Takamatsu 1 , Hideki Nakano 1 , Tetsuro Oshika 1 1Dept of Ophthalmol,Inst of Clin Med,Univ of Tsukuba pp.1515-1519
Published Date 2005/9/15
DOI https://doi.org/10.11477/mf.1410100138
  • Abstract
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A 35-year-old man presented with night blindness since 3 weeks before. His mother and brother had had colon cancer secondary to familial colon polyposis. He had received total resection of colon and partial resection of small instestine 4 years before. He showed normal findings regarding visual acuity,cornea and the fundus. Final threshsold of dark adaptation was elevated by 4 log units above normal. Electroretinogram(ERG)showed severe rod dysfunction. Serum vitamin A level was very low at 7 IU/dl. These findings led to the diagnosis of vitamin A deficiency due to malabsorption. Subjective night blindness disappeared 3 days after peroral vitamin A at the daily dosis of 3,000 IU. After 6 weeks of treatment,dark adaptation was moderately improved with no ERG changes. The patient died of liver metastasis 4 months after his initial visit.


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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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