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Cerebral Blood Flow Increase and P300 Latency Prolongation by Intravenous Injection of Acetazolamide: Investigation in Lacunar Cerebral Infarction and Healthy Subjects Minoru Oishi 1,2 , Yoko Mochizuki 1 , Motohiko Hara 1 , Toshiaki Takasu 1 1Department of Neurology, Nihon University School of Medicine Keyword: acetazolamide , cerebral blood flow , P300 , lacunar cerebral infarction , xenon CT pp.975-979
Published Date 1995/10/1
DOI https://doi.org/10.11477/mf.1406900854
  • Abstract
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The cerebral blood flow and the P300 were mea-sured before and 20 minutes after intravenous injec-tion of 17mg/kg acetazolamide in 15 cases of lacunar cerebral infarction and 10 healthy subjects. In cerebral infarction, the study was performed within 2 weeks after the onset. The cerebral blood flow except the infarcted area was increased significantly by the intravenous injection of aceta-zolamide in the lacunar cerebral infarction group and the healthy subject group. The blood flow decrease around the infarcted area (intracerebral steal phenomenon) by the intravenous injection of acetazolamide was not observed in any case.


Copyright © 1995, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 2185-405X 印刷版ISSN 0006-8969 医学書院

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