Japanese

CONGENITAL ANOMALIES OF CEREBRAL ARTERY AND INTRACRANIAL ANEURYSMS Kenji Nakajima 1 , Zentaro Ito 1 , Ryushu Hen 1 , Kazuo Uemura 2 , Shigeru Matsuoka 3 1Division of Surgical Neurology,Research Institute of Brain and Blood Vessels 2Division of Radiology, Research Institute of Brain and Blood Vessels 3Division of Surgery, Tokyo Metropolitan Komagome Hospital pp.197-201
Published Date 1976/2/1
DOI https://doi.org/10.11477/mf.1406203847
  • Abstract
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It is well known that congenital anomalies suchas polycystic kidney, aortic coarctation, Marfansyndrome, Ehler-Danlos syndrome are apt to becomplicated by intracranial aneurysms. In thisreport we attempt to reveal the relation and in-cidence between cerebrovascular anomalies and intra-cranial aneurysms. The etiology of aneurysms hasbeen discussed, too. 12 cases of persistent trigeminlartery, 2 cases of persistent hypoglossal artery and11 cases of fenestration were obtained from 3841patients who were angiographically examined inour clinic for 5 years. The incidence is 0.31%,0.05% and 0.29%, respectively. Persistent tri-geminal arteries were complicated by 2 cases ofintracranial aneurysms and one case of arterivenousmalformations (AVM), persistent hypoglossal arteri-es were complicated by one case of aneurysm, andfenestrations were complicated by 2 cases of an-eurysms and one case of AVM. One case of con-genital agenesis of right internal carotid artery wasobtained which was complicated by aneurysm ofanterior communicating artery. Totally, 8 cases ofaneurysms and AVM were obtained from 26 casesof cerebrovascular anomalies (incidence 30. 8%). Onthe other hand, thalamic or caudate hemorrhagerevealed the highest incidence of complication ofintracranial aneurysms among intracerebral hema-tomas (10.7%). Compared with the incidence ofaneurysms between cerebro vascular anomalies(30.8%) and thalamic or caudate hemorrhage(10.7%), the difference is statistically significant(P<0.05). The cause of intracranial aneurysm hasnot yet been clarified. But it is well accepted thatthe defect of tunica media vasorum is most re-sponsible factor as to the occurrence of intracranialaneurysms.

We concluded that the genetic error of cerebralvessels including defect of media caused intracranialaneurysms, and this result was supported from theevidence that cerebrovascular anomalies showedstatistically high incidence of complication of intra-cranial aneurysms.


Copyright © 1976, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 2185-405X 印刷版ISSN 0006-8969 医学書院

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