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DYSCREPANCIES BETWEEN ARTERIAL RECANALIZATION AND CLINICAL IMPROVEMENT IN CEREBRAL INFARCTION Tadayoshi Irino 1 , Mamoru Taneda 1 , Takao Minami 1 1Division of cerebrovascular diseases, Hanwa Hospital pp.303-308
Published Date 1975/3/1
DOI https://doi.org/10.11477/mf.1406203679
  • Abstract
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A comparative study of clinical observation with angiographic inspection was performed in thirteen patients with major cerebral arterial occlusion. These cases comprised seven of middle and six of internal carotid arterial occlusion, who were di-agnosed following physical and angiographical find-ings within twenty-four hours of the stroke. Six were diagnosed as cerebral thrombosis due to arterio-sclerosis and seven were suspected as having cere-bral embolism associated with atrial fibrillation. Fibrinolytic agent (Urokinase) was used at eight cases.

Cerebral angiography was repeatedly performed. The first angiogram was done within twenty-four hours of acute onset, and the second after three days or/and seven days of the stroke to inspect whether recanalization of the occluded artery oc-cured or not. Clinical observation was based on the three clinical points, consciousness, muscle strength and aphasia.

Consequently, three of internal and four of middle cerebral arterial occlusion were demonstrated re-canalization angiographically within seven days of their stroke. Not all of the cases with recanal-ization received fibrinolytic therapy. These seven cases showed no clinical improvement in spite of their angiographical restration to normal circulation.Among the remaining six cases without recanal-ization, two could return to normal social life after two months of stroke.

Thus from the data mentioned above, it can be seen apparently that recanalization therapy has no sufficient clinical effect in acute apoplectic patients suffering from cerebral infarction.


Copyright © 1975, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 2185-405X 印刷版ISSN 0006-8969 医学書院

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