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Brain and Nerve No to Shinkei Volume 25, Issue 7 （July 1973）

Brain and Nerve 脳と神経 25巻7号（1973年7月発行）

Japanese English

症例報告

食道癌の脳転移—その2治験例 BRAIN METASTASIS OF ESOPHAGEAL CANCER TWO SUCCESSFUL REMOVAL CASES 西島洋司 ¹ , 佐藤壮 ¹ , 岩淵隆 ¹ Yoji Nishijima ¹ , So Sato ¹ , Takashi Iwabuchi ¹ ¹東北大学脳疾患研究施設脳神経外科 ¹Division of Neurosurgery, Institute of Brain Diseases, Tohoku University School of Medicine pp.915-919

発行日 1973年7月1日 Published Date 1973/7/1

DOI https://doi.org/10.11477/mf.1406203350

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Abstract 文献概要
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はじめに

　転移性脳腫瘍の全脳腫瘍に対する割合は，諸家の統計によれば3〜18％とされている^{1）2）4）5）7）10）11）15）〜17）}。その原発巣は肺癌，乳癌などが多く転移性脳腫瘍全体の過半数を占めている^{3）〜6）8）10）13）15）}。しかし食道癌の脳転移は非常に少なく，本邦では現在まで我々の知り得る限りでは，文献的に2例の報告をみるにすぎない^8）10）。最近我我は食道癌の根治手術後ある期間を経て脳に転移を来たし，開頭により転移巣の摘出術を行なつた2例を経験したので，若干の文献的考察を加えて報告する。

Two successful removal cases of brain metastasis following resection of the lower esophageal cancer were reported. The first case was 45-year-old man who suffered from headache and gait disturbance 11 months after the surgery for esophageal cancer following postoperative radiation of 6,000r with Lineac acceleration. The metastatic brain tumor weighning 50 gm of the right parietal region was squamous cell cancer. As a supplementary treated, antineoplastic "Bleomycin" was given intraven-ously, 300 mg in total. This patient is living well and walks by himself at present, 2 months after the brain surgery.

The second case was 44-year-old man, who suf-fered from headache and hemiparesis of left side 5 months after the radical resection of the intra-thoracal esophageal cancer and postoperative radia-tion of 6,000r with tele ⁶⁰Co. Solitary metastatic brain tumor weighning of 50 gm was removed successfully from the the right motor area by craniotomy. Histological picture was squamous cell cancer. Intravenous administration of Bleo-mycin, 300 mg in total was also added and irradia-tion was done 5,500 r with Lineac accelerator for operated lesion. This patient is living well in satisfactory condition at present after 15 months after the brain surgery.

In these both cases, severe hemiparesis and/or intracranial hypertension were apparently improved or almost disappeared after brain surgery. Modern evolution of esophageal cancer surgery might give us a chance to encounter a brain metastasis, as a result of prolongation of the patients' life.

As a conclusion, we think brain metastasis fol-lowing successful resection of esophageal cancer has to be removed positively, if it is decided that the brain lesion can be removed safely.