所謂alveolar soft-part sarcomaの脳転移の1摘出例

CEREBRAL METASTASIS OF ALVEOLAR SOFT PART SARCOMA (CHEMODECTOMA) REPORT OF A CASE WITH REVIEW OF LITERATURE

はじめに

　alveolar soft-part sarcomaは，1952年，Christphe—rson^3）等が，四肢筋肉に好発し，その組織由来は不明であるが，極めて特徴的な組織像を呈する腫瘍に対し暫定的に命名したものである。またparagangliomaとの異同が論じられ^6）28），経過は長いが肺や脳にしばしば転移する腫瘍でもある。最近，われわれは胸部に主病変を有し，脳転移により左半身不全麻痺をきたしたalveolar　soft-part sarcomaの1例に対し，脳転移巣を摘出し，軽快，退院せしめ得たので報告する。

Alveolar soft part sarcoma is a rare disease. This report described a 32-year-old man with alveolar soft part sarcoma presumably originating in the right sided axillary lymphnode and metastasizing to the bilateral lungs, and also to the motor cortex of the right cerebral hemisphere. Two lesions of the cerebral metastases of 8gm and 18.4gm in weight were surgically removed. Following this surgery, several kinds of antineoplastic agents such as 5 FU (5-fluorouracil) of 250mg × 32, "Toyo-mycin" (Chromomycin A₃) of 500 r× 32 and Vin-blastine of 53.0 mg in total dosis were used. The patient showed clinical improvement and is well enjoying his home life 8 months after the craniotomy despite of having multiple, at least 7, abnornal round shadows measuring 24 to 70mm in diameter on chest x-ray film. An additional brief review of the cases previously reported was presented.