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Japanese

TWO CASES OF PRIMARY MALIGNANT TERATOMA OF THE BRAIN Masahisa MATSUMOTO 1 , Hiroshi HATANAKA 2 , Hiroshi MIYAKE 2 , Masayoshi TAKAHASHI 3 1Depts. of Neurosurgery, Central Railway Hospital 2Depts. of Neurosugery, Tokyo Univ., School of Med. 3Depts. of Clinical Pathology, Central Railway Hospital pp.837-850
Published Date 1966/8/1
DOI https://doi.org/10.11477/mf.1406202099
  • Abstract
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1) Two cases, 7-year-old boy and 21-year-old male, with primary malignant teratoma of the brain are presented.

Clinically precocious puberty was observed in the former case, and marked emaciation due to the hy-pothalamico-hypophysial hypofunction in the latter case.

2) Referring to the literatures, in some of the primary malignant teratomas of the brain associated with precocious puberty, it is considered that the tumor cells themselves produce plenty of chorionic gonado-tropin.

Those hormonal findings appear to be different from those of the constitutional or essential precocious puberty, so it was postulated that precocious puberty due to some of the intracranial malignant teratomas should be separated from the essential precocious puberty.

3) Cardiac disturbances including sinus arhythmia, ST changes and A-V block were observed in the both cases.

The relation of the cause of those phenomena to the central nervous system was discussed.

4) Marked hyperplasia of the bronchial basal cells was verified in the first case, which was possibly due to massive steroid therapy.


Copyright © 1966, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 2185-405X 印刷版ISSN 0006-8969 医学書院

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