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Japanese

HISTOPATHOLOGICAL STUDY ON THE BRAIN OF TUBEROUS SCLEROSIS Hideo FUJII 1 , Reiji IIZUKA 2 , Takashi SUZUKI 2 , Kotaro YAMAMURA 3 2Dep. of Neuropsychiatry, Hokkaido Univ. School of Med. 3Watanabe Hospital pp.53-62
Published Date 1965/1/1
DOI https://doi.org/10.11477/mf.1406201765
  • Abstract
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Pathological study of a 33-year-old female with typical symptoms of tuberous sclerosis, who died after surgical operation for the kidney tumor, revealed following findings:

1) Histological examination disclosed that the main component of the ventricular tumor was spongioblast. The kidney tumor was angiomyolipoma and the adenoma sebaceum was Winkler's Pringle type.

2) Morphological characteristics of giant cells and dysgenetic cells in the tuberous part of the endbrain were discussed.

3) A group of undeveloped young cells were noted around the blood vessel at the heterotopia in the white matter.

4) Argyrophilic round structureless substances were found in the molecular layer with servere marginal gliosis and as well as in the deep layer of the tuberous cortex by means of Tsujiyama's glial fibre staining.

5) Nuclei and perikarya of giant cells and glias in or near the turberous part of the endbrain were found to be PAS-positive.


Copyright © 1965, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 2185-405X 印刷版ISSN 0006-8969 医学書院

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