Japanese
English
- 有料閲覧
- Abstract 文献概要
- 1ページ目 Look Inside
著者は,定型的ナルコレプシーが5例に発現した一家系を臨床的及び遺伝的に調査して次の如く考察した。即ち,定型的ナルコレプシーは同型遺伝の傾向が強く,優性遺伝型式であり,各種内因性精神病とは独立した疾患であろう。そして表現がある程度動揺し,男性は女性に比して重症であった。
Whether the so-called endogenous narcolep-sy is a nosological entity or whether it is only a syndrom which develops on the basis of a certain abnormal constitution is still open to question. And the symptom of the narcolepsy is polymorph and its extent is obscure, but (according to Wilder) it is said that typical narcolepsy should always have sleep fit and cataplexy.
A family including 5 cases of typical nar-colepsy was studied from the clinico-geneti-cal point of view.
Each of cases (a mother, a daughter, and three sons) had similar clinical feature show-ing "halluzinatorisch-kataplektisches Augst-syndrom" (Rosenthal), various autonomic disorders and high palate, besides sleep fit and cataplexy. But narcoleptic syndrom was more severe and its onset was earlier in ma-les than females. Anamnestically, there were no diseases which might be the cause of symptomatic narcolepsy.
Furthermore, in this family there were no consanguinities and any other nervous and mental diseases. Therefore, the hereditary nature of this family-narcolepsy has a tend-ency to homotypy and dominance, but its expression varies to some extent.
Copyright © 1960, Igaku-Shoin Ltd. All rights reserved.