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Brain and Nerve No to Shinkei Volume 3, Issue 4 （July 1951）

Brain and Nerve 脳と神経 3巻4号（1951年7月発行）

Japanese English

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老年者の神經疾患に關する臨床病理解剖學的研究—第3報　老年者腦所見の統計的觀察 Clinico-Pathological Studies on the Nervous Disease of the Aged.:3.Statistical Observations of the Brain 椿忠雄 ^1,2 Tsubaki, Tadao ^1,2 ¹東京大學醫學部冲中内科教室 ²浴風會 ¹Medical Clinic of School of Medicine, University of Tokyo pp.229-231

発行日 1951年7月1日 Published Date 1951/7/1

DOI https://doi.org/10.11477/mf.1406200211

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Abstract 文献概要
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1．緒言

　我々は前報に於て，老年者に於てはかなりの高率に神經症状の出現すること，更に之等の症状は高血壓及び腦動脈硬化と著明な相關關係を有することを述べた。本報に於ては，更に前記材料の病理解剖所見より，腦所見を統計的に觀察した。即ち我々は先ず老年者の腦重量，腦動脈硬化度の年齢的分布を觀察し，次いで腦内病變の種類，傷害部位，傷害頻度を觀察し，最後に腦の血管性變化と腦重量との關係を觀察した。老年性腦變化については，既に先人により各種の研究が爲されているが，之等は少數例について行われたものであり，且つ特殊の集團によるものが多いのに反し，我々の統計は，極めて多數例について行つたものであり，且つ本材料の性質より考えて，本統計は，一般老年者の死亡時腦所見に該當すると思われる。

The pathologic anatomical Studies have been made on the brains of about 800 cases and the followings are the results obtained from sta-tistical standpoint.

1) As shown in table I, the weight of the persons over 60 years of age tends to decrease gradually corresponding to the ages, though this is not a distinct phenomen.

2) The observation of the cerebral arteries revealed that there was a significant defference in the degree of arteriosclerosis between sixty agers and seventy agers and no significant one between seventy agers and eighty agers.

3) The degree of the cerebral arteriosclerosis is in parallel with those of the aortic and coronary sclerosis.

4) Noticeable lesions were found in 352 cases (43 per cent of 818 cases). Of these, there were 326 non-hemorrhagic softenings, 118 hemorrha-ges, 55 hemorrhagic softenings and 30 Etat lacunaire or Etat cribre. The frequency of lesions according to their localization is as follows. 204 cases in or near striatum, 71 cases in cerebral cortex, 60 cases in thalamus, 51 cases in internal capsule, 40 cases in pons, 36 cases in white matter of cerebrum and 67 cases in the other places.

5) The decrease of the weight of the brains has a close correlation to the cerebral arteri-osclerosis. And in cases with moderately adv-anced cerebral arteriosclerosis, the decrease of the weight of the brain of the persons with hypertension was found sligoter than that of others. However, in cases with relatively slight cerebral arteriosclerosis, there was no relatio-nship between the hypertension and the decr-ease of the weight of the brains.