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Temporal Changes of Diffusion-weighted MR Images in a Patient with Transient Global Amnesia Yusuke Matsui 1 , Hidemoto Saiki 1 , Hidekazu Tomimoto 1 , Ryosuke Takahashi 1 , Yukio Miki 2 , Hidenao Fukuyama 3 1Department of Neurology, Graduate School of Medicine, Kyoto University 2Department of Diagnostic Imaging and Nuclear Medicine, Graduate School of Medicine, Kyoto University 3Human Brain Research Center, Graduate School of Medicine, Kyoto University Keyword: transient global amnesia , diffusion-weighted image , MRI , transient ischemic attack , hippocampus pp.991-995
Published Date 2005/11/1
DOI https://doi.org/10.11477/mf.1406100099
  • Abstract
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The pathogenesis of transient global amnesia (TGA) remains uncertain, although it is featured by characteristic clinical symptoms. We present a patient with TGA, in which diffusion-weighted MR image showed a punctuate hyperintense lesion in the left CA1 subfield of the hippocampus adjoining the lateral ventricle 24 hours after the onset. This lesion was observed with FLAIR image after 9 days from the onset, and therefore was considered to be a delayed ischemic lesion. A SPECT and PET studies 7 days after the onset showed a decrease of the CBF, CMRO2 and CMRglu, and was compatible with a delayed ischemic lesion. However, there were no cardiovascular risk factors nor abnormalities of vascular supply, and therefore the reason for microcirculatory disturbances remained unclear.

(Received : February 2, 2005)


Copyright © 2005, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 2185-405X 印刷版ISSN 0006-8969 医学書院

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