Three Cases of Idiopathic Pause-dependent Long QT Syndrome in the Elderly Jin-woo Kim 1 , Megumi Shimada 1 , Shigenori Kiguchi 1 , Shinji Ito 1 , Michiko Takahashi 1 , Hideyo Shimada 1 , Makoto Akaishi 1 1Department of Internal Medicine, Kitasato Institute Hospital Keyword: QT延長症候群 , 休止期依存 , torsade de pointes , 高齢者 , long QT syndrome , pause-dependent , torsade de pointes , old age pp.199-203
Published Date 2000/2/15
DOI https://doi.org/10.11477/mf.1404902049
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We report three elderly female patients with pause-dependent long QT syndrome (LQTS) which werediagnosed when they passed the age of 60. One was 80years old, another was 65 years old and the other was 81years old. They had not suffered from any other car-diovascular disease. However, the 80-year-old womanhad been prone to syncope since she was approximately20 years old. The ether two had been free from syncope.All of them were admitted to our department because ofsyncope. At that time, their electrocardiograms showedprolongation of QT interval (QT intervals 0.55 sec, 0.52sec, 0.52 sec), and also ventricular tachycardia, the socalled torsade de pointes. First of all, we gave themXylokine and Mg-sulfate intravenously, after that, weimplanted permanent pacemakers. Their laboratoryfindings showed almost normal range includingelectrocytes (Na, K, Cl, Mg). The causes for theirsyncope were neither heriditary nor drug-induced, so wesupposed that the causes were due to idiopathic factors.The common characteristics were that all of them werewomen more than 60 years old, whose syncope dependedon the pauses after ventricular premature heart beat.Considering these factors, we concluded that they wereall rare cases.

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