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Improvement of Myocardial Perfusion Detected by 201Tl Scintigraphy on Cardiac Rehabilitation for Patients with Coronary Artery Disease Linxue Li 1 , Ryuij Nohara 1 , Shigeru Makita 1 , Tatsuhiko Hata 1 , Ryohei Hosokawa 1 , Kazumi Okuda 2 , Hiroshi Hamazaki 3 , Masaaki Shimomura 3 , Masatoshi Fujita 4 , Shigetake Sasayama 1 1Third Division, Department of Internal Medicine, Kyoto University Hospital 2Red Cross Hospital, Osaka 3Study Group of Cardiac Sports Rehabilitation, Kyoto University 4College of Medical Technology, Kyoto University Keyword: 冠動脈疾患 , 運動療法 , 201Tl心筋SPECT , coronary artery disease , cardiac rehabilitation , 201Tl SPECT pp.745-752
Published Date 1996/7/15
DOI https://doi.org/10.11477/mf.1404901292
  • Abstract
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The effect of cardiac rehabilitation (mean 70±48 months) on myocardial perfusion was assessed using thallium-201 (201T1) exercise study in 63 patients with coronary artery disease (CAD). Subjects were those in a rehabilitation group (Rh=42) participating in super-vised sports training two to three times per week and the control group (Ct=21) not taking active daily exercise. The interval between two 201T1 SPECTstudies was 19±16 months. After physical training, total duration of the exercise test increased from 443± 112 to 536±121 seconds (+19%) in the Rh group, and from 481±129 to 432±115 seconds in the Ct group (-10.7%) (p<0.01). Peak double products increased from 203.4 ± 72×102 to 269.8±58x10' in the Rh group and decreased from 218.7±40×102 to 216.6±76×102 (p<0.01) in the Ct group. 201Tl myocardial perfusion defect on exercise improved more in 54.8% (stress 59. 5%, rest 35.7%) in the Rh group than in the Ct group (9. 5%, p<0.01). 201T1 perfusion defect decreased from 68 (23.1%) to 49 regions (16.7%) of 294 total myocardial regions in the Rh group on exercise. However, it in-creased from 39 (26.5%) to 44 (29.9%) regions of 147 regions in the Ct group (p<0.01). Thus, cardiac rehabil-itation increases exercise tolerance with improvement of myocardial perfusion, suggesting that cardiac reha-bilitation is an advisable and effective treatment for patients with ischemic heart disease.


Copyright © 1996, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1200 印刷版ISSN 0452-3458 医学書院

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