Bronchial Hyperresponsiveness in Syndrome X Masanobu Namura 1 , Hohnin Kanaya 1 , Masatoshi Ikeda 1 , Shinsuke Shibayama 1 , Koh-ichi Nishi 1 , Takio Ohka 1 1Department of Internal Medicine, Ishikawa Prefectural Central Hospital Keyword: Syndrome X , アセチルコリン , 気道過敏性 , acetylcholine , bronchial hyperresponsiveness pp.737-740
Published Date 1996/7/15
DOI https://doi.org/10.11477/mf.1404901290
  • Abstract
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We compared bronchial response to the inhalation of acetylcholine in patients presenting syndrome X with that in patients presenting vasospastic angina or effort angina using the astograph. Syndrome X had a lower Dmin (cumulative inhalation dose of acetylcholine at the initial stage of decrease in airway conductance Grs), the index of bronchial sensitivity, than other angina cases. On the other hand, Grs-c (initial value of the airway conductance) or SGrs/Grs-c (corrected value of Grs decrease rate divided by Grs-c), the index of bronchial reactivity, did not differ significantly whether in syndrome X cases or in other angina cases. These data suggest that syndrome X has bronchial hyperresponsiveness based on bronchial hypersen-sitivity, not on hyperreactivity, thus differing from bronchial asthma.

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