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Characteristics of Plasma Levels of Myosin Light Chain Ⅰ in Patients under Aorta-Coronary Bypass Grafts Takeshi Tanaka 1 , Keiichi Aoki 1 , Tadanori Aizawa 1 , Kazuzou Katou 1 , Shuichirou Takanashi 1 , Shoichi Huruta 1 1The Cardiovascular Institute Keyword: 心筋ミオシン軽鎖Ⅰ , バイパス手術 , 術中心筋障害 , myosin light chain I , aorta-coronary bypass grafts , perioperative myocardial injury pp.451-457
Published Date 1993/5/15
DOI https://doi.org/10.11477/mf.1404900665
  • Abstract
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After cardiac operation plasma level of ventricular myosin light chainⅠ(LCI), determined with monoclonal antibodies to myosin fragment, were studied in 30 patients under bypass surgery to assess its possible role as a marker for perioperative myocardial injury. LCI rapidly increased and reached peak levels (15.8± 9.0 gn/ml; T-peak) at 88±28 minutes after aortic de-clamp (T-Time). Then LCI rapidly decreased with fast half-time disappearance (1.1±0.7 hours). In 7 out of 30 patients LCI improved to normal range and MB reached maximum levels (28.8±11.9 U/L) at 6.3±2.3 hours after declamp.


Copyright © 1993, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1200 印刷版ISSN 0452-3458 医学書院

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