雑誌文献を検索します。書籍を検索する際には「書籍検索」を選択してください。

検索

書誌情報 詳細検索 by 医中誌

Japanese

Studies on evaluation of the oxygen transport system function with multistage treadmill stress testing:Comparison between normal control subjects and patients with coronary heart disease Nobutaka Doba 1 , Toshio Kushiro 2 , Hiroshi Tomiyama 2 , Noriaki Hayashida 3 , Akira Yamashina 3 , Hiroyuki Abe 4 , Shigeaki Hinohara 5 1The 3rd Department of Internal Medicine, Teikyo University School of Medicine 2Department of Cardiology, Surugadai Hospital, Nihon University School of Medicine 3Department of Internal Medicine, St. Luke's International Hospital 4Department of Radiology, Itabashi Hospital, Nihon University School of Medicine 5The Life Planning Center pp.785-789
Published Date 1989/7/15
DOI https://doi.org/10.11477/mf.1404205513
  • Abstract
  • Look Inside

 The oxygen transport system (OTS) function was evaluated with multistage treadmill stress testing on 171 normal control subjects and 80 patients with coronay heart disease (CHD). After Bruce's definition, OTS function was expressed with functional aerobic impairment (FAI), left ventricular impairment (LVI) or myocardial aerobic impairment (MAI), heart rate impairment (HRI) or chronotropic reserve impairment (CRI) and peripheral circulatory impairment (PCI). All subjects were monitored on heart rate, blood pressure, electrocardiogram and endtidal O2 and CO2 before and every one minute during the symptom limited maximal stress testing. Seventy three of 80 coronary patients were sujected to the coronary arteriography and were classified into four groups ; 31 with single vessel disease (SVD), 20 with double vessel disease (DVD), 15 with tripple vessel disease (TVD) and 7 with A-C bypass surgery. Comparison between normal control subjects and the CHD patients with regard to the relation of age and Vo2max derived from the linear regression analysis disclosed the identical age-related decrease in Vo2maa in both groups. The age corrected Vo2max in the CHD patients, however, was 2. 2 METS less than that of normal control subjects. Therefore, the level of Vo2max in CHD patients was determined not only by disease, but also by ageing process itself. Comparisons among three CHD groups with regard to FAI, LVI, HRI and PCI clearly demonstrated different functional impairments paralleling to the severity of the disease process. On the other hand, the patients with A-C bypass surgery revealed almost identical functional impairment to the patients with SVD. In conclusion, these simple and noninvasive evaluations of the oxygen transport system could give us valuable informations reasonably differntiating the clinical status of the patients with CHD.


Copyright © 1989, Igaku-Shoin Ltd. All rights reserved.

基本情報

電子版ISSN 1882-1200 印刷版ISSN 0452-3458 医学書院

関連文献

もっと見る

文献を共有